The Ultimate Creamy Ground Beef Casserole with Penne

By Emily

On March 25, 2026

Ingredients for ground beef casserole including penne pasta, fresh herbs, cheese, and ground beef on a marble tabletop.

Cuisine

American

Prep time

15 minutes

Cooking time

25 minutes

Total time

40 minutes

Servings

6 people

This Ground Beef Casserole is the ultimate comfort food for busy weeknights. Imagine ladling a hearty serving of perfectly seasoned ground beef and tender penne pasta into a shallow, light gray ceramic bowl. Every single bite is generously coated in a thick, creamy melted cheddar cheese sauce.

There is something incredibly satisfying about combining savory beef with a velvety, from-scratch cheese sauce. The aroma alone will bring everyone to the table before the dish even leaves the oven. Finished with bright flecks of finely chopped parsley, this casserole looks like it belongs in a food magazine.

Whether you cook it in a trusty yellow cast iron pot or a standard baking dish, it delivers warm and inviting flavors. It is a photorealistic masterpiece of home cooking that will quickly become a family favorite.

Why You’ll Love This Recipe

  • Velvety Cheddar Cheese Sauce: Forget canned soups; this thick, creamy melted cheddar cheese sauce coats every piece of pasta perfectly.
  • Hearty and Satisfying: The combination of seasoned ground beef and filling penne pasta makes this a meal that truly satisfies hungry appetites.
  • Visually Stunning: With a golden, bubbly top and fresh green flecks of finely chopped parsley, it looks just as incredible as it tastes.
  • Perfect for Meal Prep: This casserole reheats beautifully, making it an excellent option for leftovers throughout the week.

Ingredients & Substitutions

A shallow light gray ceramic bowl filled with creamy ground beef and penne pasta casserole, resting on a folded yellow linen napkin.
A hearty serving of warm, cheesy Ground Beef Casserole sprinkled with fresh parsley.

Penne Pasta: You will need 12 oz (340g) of dried penne pasta for the base. The tubular shape is perfect for holding onto the thick, creamy melted cheddar cheese sauce.

Ground Beef: Use 1 lb (450g) of lean ground beef (80/20 is ideal) for the best flavor. This provides a robust, meaty foundation that contrasts beautifully with the rich cheese.

Aromatics: 1 medium yellow onion (diced) and 3 cloves of minced garlic build the savory flavor profile. They are foundational ingredients required to give the beef depth.

Seasonings: Use 1 tsp (5g) salt, 1 tsp (2g) black pepper, and 1 tbsp (7g) paprika. These spices create the perfectly seasoned ground beef crust you see in the final dish.

Butter & Flour (Roux): You need 3 tbsp (42g) unsalted butter and 3 tbsp (24g) all-purpose flour. Cooking these together creates the thickening base required for the cheese sauce.

Whole Milk: Slowly whisking in 2 cups (480ml) of whole milk transforms the roux into a smooth, creamy liquid. Whole milk ensures the highest quality texture.

Sharp Cheddar Cheese: Freshly grate 2 cups (226g) of sharp cheddar cheese from a block. Pre-shredded cheese contains anti-caking agents that will prevent a perfectly smooth melt.

Fresh Parsley: You will need 2 tbsp (8g) of finely chopped fresh parsley. These bright green flecks sprinkled on top provide a crucial visual pop and fresh herbaceous flavor.

Equipment Needed

  • A large yellow cast iron pot or Dutch oven for browning the beef and building the sauce.
  • A separate large pot for boiling the penne pasta.
  • A sturdy balloon whisk for creating a lump-free cheese sauce.
  • A box grater for shredding the cheddar cheese to ensure a flawless melt.
  • Shallow, light gray ceramic bowls for an elegant, photorealistic serving presentation.

Step-by-Step Instructions

1. Boil the Penne Pasta

Bring a large pot of heavily salted water to a rolling boil. Add 12 oz (340g) of penne pasta and cook for 8-9 minutes until it reaches al dente. Drain the pasta well and set it aside, ensuring it retains a slight chew to hold up in the casserole.

2. Sear the Seasoned Ground Beef

Ingredients for ground beef casserole including penne pasta, fresh herbs, cheese, and ground beef on a marble tabletop.
Everything you need to make the ultimate creamy Ground Beef Casserole.

Heat a large cast iron pot over medium-high heat. Add 1 lb (450g) of ground beef, the diced yellow onion, and minced garlic. Season immediately with 1 tsp (5g) salt, 1 tsp (2g) black pepper, and 1 tbsp (7g) paprika.

Break the meat apart with a wooden spoon and sear until a deep golden-brown crust forms and no pink remains. Drain any excess grease from the pot and transfer the seasoned beef to a separate plate.

3. Build the Thick Creamy Cheese Sauce

In the same cast iron pot, lower the heat to medium and melt 3 tbsp (42g) of butter. Whisk in 3 tbsp (24g) of all-purpose flour and cook for 1-2 minutes until it smells lightly toasted. This roux is the critical foundation for your thick sauce.

Slowly pour in 2 cups (480ml) of whole milk, whisking constantly to prevent lumps. Simmer for 3-4 minutes until the liquid thickens enough to coat the back of a spoon.

4. Melt the Cheddar and Combine

Remove the pot from the heat completely to prevent the cheese from separating. Gradually whisk in 2 cups (226g) of freshly grated sharp cheddar cheese until you achieve a thick, creamy melted cheddar cheese sauce. Fold the cooked penne and the seasoned ground beef into the luscious sauce until fully combined.

5. Bake and Garnish

If your pot is oven-safe, smooth the mixture out; otherwise, transfer it to a baking dish. Bake at 375°F (190°C) for 10-15 minutes until the edges are bubbling and the top is warm and inviting. Remove from the oven and immediately sprinkle with flecks of finely chopped parsley before ladling into shallow ceramic bowls.

Expert Tips for Success

  • Grate your own cheese: Always shred cheddar from a block. Pre-bagged cheese contains starches that make the melted cheese sauce grainy instead of silky.
  • Do not rinse the pasta: Leaving the residual starch on your boiled penne helps the thick creamy cheddar cheese sauce cling to every noodle.
  • Whisk the milk slowly: When building your roux, add the milk in a slow, steady stream while whisking vigorously to guarantee a perfectly smooth texture.
  • Remove from heat before adding cheese: Adding cheese to a boiling sauce will cause the dairy proteins to break and become oily. Always pull the pot off the burner first!

Storage & Reheating/Freezing

Store any leftover ground beef casserole in an airtight container in the refrigerator for up to 4 days. The flavors often meld and taste even better the next day.

To reheat, add a splash of milk (about 1 tbsp (15ml) per serving) and microwave in short bursts, stirring frequently to revive the creamy cheese sauce. If freezing, allow the casserole to cool completely, wrap tightly, and freeze for up to 3 months.

What to Serve With This

This hearty pasta bake pairs beautifully with a side of warm garlic herb dutch oven bread to soak up any remaining cheese sauce. For a burst of green vegetables, serve it alongside sauteed zucchini and mushrooms.

If you are hosting a larger gathering, kick the meal off with a bubbling spinach artichoke dip. If you have guests who prefer poultry, consider offering perfect roast chicken as an alternative main course on your dinner table.

Frequently Asked Questions

Yes, this dish freezes beautifully. Let the cooked casserole cool completely, wrap it tightly with plastic wrap and aluminum foil, and store it in the freezer for up to 3 months. Thaw overnight in the refrigerator before reheating.

Absolutely! You can assemble the casserole completely, let it cool, cover it tightly, and refrigerate it for up to 24 hours before baking. You may need to add 5-10 extra minutes to the baking time if cooking right from the fridge.

Yes, it is highly recommended to drain the excess grease from the cast iron pot after browning the beef. Leaving too much fat in the pan can make your thick, creamy cheese sauce oily and cause it to separate.

If you don’t have penne, you can substitute it with any short, tubular pasta like ziti, rigatoni, or macaroni. These shapes are perfect for holding onto the thick, melted cheddar cheese sauce.

Grainy cheese sauce usually happens for two reasons: using pre-shredded cheese (which contains anti-caking agents) or adding the cheese while the sauce is still boiling on the stove. Always use freshly grated block cheese and remove the pot from the heat before whisking it in.

Ready to Dig In?

This Ground Beef Casserole is guaranteed to become a regular in your dinner rotation. The combination of savory beef, tender penne, and rich cheddar sauce is entirely irresistible.

If you loved this recipe, please leave a comment and a 5-star review below! Don’t forget to subscribe to our newsletter for more comforting dinner recipes, and pin this image to your favorite Pinterest board so you can easily find it later.

Recipe Card

Ingredients for ground beef casserole including penne pasta, fresh herbs, cheese, and ground beef on a marble tabletop.

The Ultimate Creamy Ground Beef Casserole with Penne

This ultimate Ground Beef Casserole features seasoned beef and penne pasta smothered in a thick, creamy melted cheddar cheese sauce. It is a hearty, visually stunning comfort food dinner that your whole family will absolutely love.
Prep Time 15 minutes
Cook Time 25 minutes
Total Time 40 minutes
Servings: 6 people
Course: Dinner, Main Course
Cuisine: American
Calories: 580

Ingredients
  

Main Ingredients
  • 12 oz Penne pasta 340g, dried
  • 1 lb Lean ground beef 450g, 80/20 preferred
  • 1 medium Yellow onion Diced
  • 3 cloves Garlic Minced
  • 1 tsp Salt 5g
  • 1 tsp Black pepper 2g
  • 1 tbsp Paprika 7g
  • 3 tbsp Unsalted butter 42g
  • 3 tbsp All-purpose flour 24g
  • 2 cups Whole milk 480ml
  • 2 cups Sharp cheddar cheese 226g, freshly grated
  • 2 tbsp Fresh parsley 8g, finely chopped

Equipment

  • 1 Cast Iron Pot or Dutch Oven Used for browning beef and building the cheese sauce.
  • 1 Balloon Whisk Essential for creating a smooth, lump-free roux.
  • 1 Box grater For freshly shredding the cheddar cheese.

Instructions
 

Cooking Instructions
  1. Bring a large pot of heavily salted water to a rolling boil. Add 12 oz (340g) of penne pasta and cook for 8-9 minutes until it reaches al dente. Drain the pasta well and set it aside, ensuring it retains a slight chew to hold up in the casserole.
  2. Heat a large cast iron pot over medium-high heat. Add 1 lb (450g) of ground beef, the diced yellow onion, and minced garlic. Season immediately with 1 tsp (5g) salt, 1 tsp (2g) black pepper, and 1 tbsp (7g) paprika. Break the meat apart with a wooden spoon and sear until a deep golden-brown crust forms and no pink remains. Drain any excess grease from the pot and transfer the seasoned beef to a separate plate.
  3. In the same cast iron pot, lower the heat to medium and melt 3 tbsp (42g) of butter. Whisk in 3 tbsp (24g) of all-purpose flour and cook for 1-2 minutes until it smells lightly toasted. Slowly pour in 2 cups (480ml) of whole milk, whisking constantly to prevent lumps. Simmer for 3-4 minutes until the liquid thickens enough to coat the back of a spoon.
  4. Remove the pot from the heat completely to prevent the cheese from separating. Gradually whisk in 2 cups (226g) of freshly grated sharp cheddar cheese until you achieve a thick, creamy melted cheddar cheese sauce. Fold the cooked penne and the seasoned ground beef into the luscious sauce until fully combined.
  5. If your pot is oven-safe, smooth the mixture out; otherwise, transfer it to a baking dish. Bake at 375°F (190°C) for 10-15 minutes until the edges are bubbling and the top is warm and inviting. Remove from the oven and immediately sprinkle with flecks of finely chopped parsley before ladling into shallow ceramic bowls.

Notes

Always grate your own cheddar cheese from a block for a silky smooth sauce.
Remove the pot from the heat before adding the cheese to prevent the dairy from breaking and becoming oily.
A close-up view of Ground Beef Casserole with penne pasta coated in creamy cheddar cheese sauce and garnished with chopped parsley.
Hearty and comforting Ground Beef Casserole made with a thick, velvety cheddar cheese sauce.

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